Related Experiment Videos
[Primary brain tumors in children. I].
C Carrie1, E Bouffet, M Brunat-Mentigny
1Service de radiotherapie, centre Léon-Bérard, Lyon, France.
Bulletin Du Cancer
|January 1, 1989
Summary
Pediatric brain tumors are common and have poor prognoses despite treatment advances. This review details common symptoms, signs, and recent diagnostic and therapeutic progress in pediatric central nervous system tumors.
Area of Science:
- Pediatric Oncology
- Neuro-oncology
- Clinical Pediatrics
Context:
- Central nervous system (CNS) tumors are the most common pediatric solid tumors.
- Despite advances in neurosurgery, radiotherapy, and chemotherapy, outcomes remain challenging.
- Long-term survivors often face significant late effects, including neuropsychological, endocrine, and physical issues.
Purpose:
- To outline the typical presenting symptoms and clinical signs of brain tumors in children.
- To review significant advancements in the diagnosis and treatment of pediatric CNS tumors over the last decade.
Summary:
- This first part of a series focuses on the initial clinical presentation of pediatric brain tumors.
- It highlights key developments in diagnostic modalities such as histology, immunohistochemistry, cytogenetics, and radiology.
- Recent therapeutic strategies and their impact on patient management are also discussed.
Impact:
- Provides essential information for early recognition of pediatric brain tumors.
- Updates clinicians on the latest diagnostic tools and therapeutic approaches.
- Aims to improve the overall prognosis and quality of life for children with CNS tumors.