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Updated: Apr 20, 2026

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
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[Phlegmasia cerulea dolens].

C Zeboulon1, M Amy de la Bretèque1, P Bilan1

  • 1Service de dermatologie et médecine vasculaire, centre hospitalier Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil cedex, France.

Annales De Dermatologie Et De Venereologie
|December 3, 2014
PubMed
Summary
This summary is machine-generated.

Phlegmasia cerulea dolens, a severe venous thrombosis with arterial ischemia, requires prompt diagnosis. This condition, often linked to malignancy, presents with pain, edema, and cyanosis, necessitating urgent treatment for better outcomes.

Keywords:
Arterial thrombosisLeg ulcersParaneoplastic syndromesPhlegmasia cerulea dolensPhlébite bleueSyndrome paranéoplasiqueThrombose artérielleThrombose veineuseUlcère des membres inférieursVenous thrombosis

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Area of Science:

  • Vascular Surgery
  • Hematology
  • Oncology

Background:

  • Phlegmasia cerulea dolens (PCD) is a rare, severe form of deep vein thrombosis (DVT).
  • It is characterized by extensive venous thrombosis leading to arterial compromise.
  • Malignancy is a frequent underlying cause, as seen in this case of metastatic urothelial bladder carcinoma.

Observation:

  • A 69-year-old male patient presented with bilateral lower limb trophic changes, edema, cyanosis, and ischemia.
  • Doppler ultrasound confirmed bilateral proximal deep vein thrombosis.
  • Distal arterial flow was absent, indicating severe arterial compromise.

Findings:

  • The patient was diagnosed with bilateral phlegmasia cerulea dolens.
  • The condition was associated with metastatic urothelial bladder carcinoma and arteritis.
  • The classical triad of pain, edema, and cyanosis was present.

Implications:

  • Early recognition of PCD, based on clinical signs and Doppler ultrasound confirmation, is crucial.
  • While anticoagulation is traditional, endovascular options may be considered.
  • Prompt diagnosis and treatment initiation are vital for improving the prognosis of this limb-threatening condition.