Related Experiment Video

Updated: Feb 12, 2026

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging
09:29

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging

Published on: April 28, 2017

9.9K

Multidrug resistant Fusarium keratitis

P Antequera1, V Garcia-Conca2, C Martín-González1

  • 1Servicio de Microbiología, Hospital Universitario San Juan, Alicante, España.

Archivos De La Sociedad Espanola De Oftalmologia
|December 3, 2014
PubMed
Abstract

Insights

Multiresistant Fusarium solani caused severe keratitis in a contact lens wearer, leading to corneal abscess and requiring eye enucleation despite antifungal treatment. Early diagnosis and aggressive therapy are crucial for managing this resistant fungal infection.

Area of Science:

  • Ophthalmology
  • Medical Mycology

Background:

  • Contact lens wear is a significant risk factor for microbial keratitis.
  • Fusarium species are common causes of fungal keratitis, particularly in tropical and subtropical regions.

Observation:

  • A contact lens wearer presented with a deep corneal abscess.
  • Corneal biopsy cultures identified a multiresistant strain of Fusarium solani.

Findings:

  • The patient experienced a complicated clinical course with poor response to standard antifungal treatments.
  • Despite aggressive local and systemic antifungal therapy, the infection progressed, necessitating enucleation.

Implications:

  • Fusarium keratitis can lead to severe outcomes, including endophthalmitis and vision loss.
  • The high resistance of some Fusarium strains to conventional antifungal drugs complicates treatment strategies.
  • Prompt clinical suspicion and initiation of appropriate antifungal therapy are critical for successful management of fungal keratitis.
Keywords:
Contact lensEndoftalmitisEndophthalmitisFusarium solaniKeratitisLentes de contactoQueratitis

More Related Videos

Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein10:43

Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein

Published on: December 3, 2010

22.9K
The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.7K

Related Concept Videos

Resistivity01:22

Resistivity

When a voltage is applied to a conductor, an electrical field is generated, and charges in the conductor feel the force due to the electrical field. The current density that results depends on the electrical field and the properties of the material. In some materials, including metals at a given temperature, the current density is approximately proportional to the electrical field. In these cases, the current density can be modeled as:
4.6K
Resistance01:19

Resistance

When a current moves through any conductor, the conductor causes some level of difficulty for the current to flow. The measure of that difficulty is known as the resistance of the material and is represented by R. Every material has its own resistance. In the case of conductors, heat is emitted whenever a current passes through them. Resistance depends on the resistivity of the material. Resistivity is a characteristic of the material used to fabricate electrical components, whereas the...
6.1K
Equivalent Resistance01:16

Equivalent Resistance

In circuit analysis, situations often arise where resistors are neither in series nor parallel configurations. To tackle such scenarios, three-terminal equivalent networks like the wye (Y) (Figure 1 (a)) or tee (T) and delta (Δ) (Figure 1 (b)) or pi (π) networks come into play. These networks offer versatile solutions and are frequently encountered in various applications, including three-phase electrical systems, electrical filters, and matching networks.
1000
Resistance and Conductance01:25

Resistance and Conductance

A conductor's DC resistance at a given temperature is influenced by its resistivity, length, and cross-sectional area. Resistivity is an inherent property of the conductor material, with annealed copper serving as the international standard for measurement. For instance, the resistivity of hard-drawn aluminum at 20 degrees Celsius is 61% of the standard conductivity of annealed copper.
Various factors impact the resistance of a conductor. Spiraling in stranded conductors increases their...
531
Rolling Resistance01:21

Rolling Resistance

When a solid cylinder rolls steadily on a rigid surface, the normal force applied by the surface on the cylinder is perpendicular to the tangent at the contact point. However, since no materials are entirely rigid, the surface's reaction to the cylinder involves a range of normal pressures.
For instance, imagine a hard cylinder rolling on a comparatively soft surface. The cylinder's weight compresses the surface beneath it. As the cylinder moves, the material in front of it slows down due to...
679
Vascular Resistance01:20

Vascular Resistance

Vascular resistance is a critical concept in understanding blood flow dynamics in the circulatory system. It refers to the resistance that blood encounters as it flows through the blood vessels. This resistance is a key factor in determining blood pressure and cardiac workload.
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
11.2K