Related Experiment Video
Updated: Apr 20, 2026
07:45
Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
Published on: November 6, 2018
10.4K
Cellulitis Recurrence Score: a tool for predicting recurrence of lower limb cellulitis
Evelyn Yuxin Tay1, Stephanie Fook-Chong2, Choon Chiat Oh3
1National Skin Centre, Singapore.
Journal of the American Academy of Dermatology
|December 3, 2014
Summary
Recurrent cellulitis is common. Key risk factors include lymphedema, chronic venous insufficiency, peripheral vascular disease, and deep vein thrombosis. A new score (CRS) helps predict recurrence.
Area of Science:
- Dermatology
- Infectious Diseases
- Vascular Medicine
Background:
- Cellulitis is a prevalent skin infection with a high recurrence rate.
- Understanding recurrence predictors is crucial for patient management.
Purpose of the Study:
- Identify factors associated with lower-limb cellulitis recurrence in first-episode patients.
- Develop a clinical risk score (Cellulitis Recurrence Score - CRS) to predict 1-year recurrence.
Main Methods:
- Retrospective review of 225 patients' dermatology referral forms and national records (2003-2012).
- Analysis of demographics, dermatoses, local factors, and comorbidities.
- Multivariate analysis to identify significant predictors of recurrence.
Main Results:
- 45.3% of patients experienced cellulitis recurrence.
- Lymphedema, chronic venous insufficiency, peripheral vascular disease, and deep vein thrombosis were significant predictors (P < .0005 to P = .008).
- The Cellulitis Recurrence Score (CRS) demonstrated good predictive value (PPV 83.6%, NPV 67.5% for CRS ≥ 2).
Conclusions:
- Lymphedema, chronic venous insufficiency, peripheral vascular disease, and deep vein thrombosis are key risk factors for cellulitis recurrence.
- The CRS is a reliable tool for predicting recurrence.
- Early intervention is recommended for patients with a CRS score of 2 or higher.
