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Progress towards measles elimination in Singapore
Hanley J Ho1, Constance Low2, Li Wei Ang2
1Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore.
Singapore has significantly reduced measles incidence through vaccination programs, though sporadic cases persist. Recent updates to the national immunization schedule aim for complete measles elimination by vaccinating children with two MMR vaccine doses before age two.
Area of Science:
- Public Health
- Epidemiology
- Immunization Programs
Background:
- Measles elimination is a global public health goal.
- Singapore has implemented various strategies to control measles transmission.
- Understanding epidemiological trends is crucial for assessing progress towards elimination.
Purpose of the Study:
- To analyze measles epidemiological trends in Singapore from 1981 to 2012.
- To evaluate Singapore's progress against the World Health Organization's measles elimination criteria.
- To identify remaining challenges in achieving measles elimination.
Main Methods:
- Analysis of measles epidemiological data from the Communicable Diseases Division.
- Review of measles vaccination coverage data from national registries.
- Examination of seroprevalence survey findings to assess population immunity.
Main Results:
- Measles incidence decreased significantly following the National Childhood Immunization Programme and MMR vaccine introduction.
- High vaccination coverage (95% first dose, 92-94% second dose) was maintained.
- Sporadic measles cases continue to occur in unvaccinated populations, with genotype shifts observed.
Conclusions:
- Singapore has achieved substantial progress toward measles elimination.
- The national immunization schedule was updated to include two doses of the MMR vaccine before two years of age.
- Continued vigilance and vaccination efforts are necessary to eliminate sporadic measles cases.
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