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Updated: Apr 20, 2026

In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
Evaluation and treatment of pump thrombosis and hemolysis
Vakhtang Tchantchaleishvili1, Fabio Sagebin1, Ronald E Ross1
11 Division of Cardiothoracic Surgery, 2 Department of Cardiology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Abstract:
Ventricular assist devices (VADs) are not fully biocompatible, and are therefore predisposed to device thrombosis and subsequent pump dysfunction. Clinically significant hemolysis in VADs most often occurs as a result of device thrombosis, but can also be caused by other factors. Herein we describe the evaluation and management of VAD thrombosis and hemolysis.
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