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Determination of Lipid Raft Partitioning of Fluorescently-tagged Probes in Living Cells by Fluorescence Correlation Spectroscopy FCS
Published on: April 6, 2012
A highly sensitive C3-symmetric Schiff-base fluorescent probe for Cd2+
Xiu-Juan Jiang1, Min Li, Hong-Lin Lu
1College of Chemistry and Molecular Engineering, Zhengzhou University , Henan 450001, P. R. China.
Abstract:
A new C3-symmetric Schiff-base fluorescent probe (L) based on 8-hydroxy-2-methylquinoline has been developed. As expected, the probe L can display high fluorescent selectivity for Cd(2+) over Zn(2+) and most other common ions in neutral ethanol aqueous medium. Moreover, the mechanism of the L-Cd(2+) complex has been confirmed by X-ray crystallography and density functional theory calculation results. More importantly, L could be used to image Cd(2+) within living cells.

