Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combating small extracellular vesicle-mediated immunological barriers in the tumor microenvironment via strategically activatable PEGylated peptides.

Signal transduction and targeted therapy·2026
Same author

Therapeutic Efficacy of PB101 and Chemotherapy Combination in Preclinical Gastric Cancer Models.

Anticancer research·2026
Same author

Chicken interleukin-26: characterization and antigen capture enzyme-linked immunosorbent assay.

Poultry science·2026
Same author

Correlational Validity and Biomarker Associations of the Korean Computerized Cognitive Function Test Relative to the Seoul Neuropsychological Screening Battery in MCI and Alzheimer's Disease.

Dementia and geriatric cognitive disorders·2026
Same author

Carboxymethylated cellulose nanofibers as rheological regulators for electrically anisotropic liquid metal bilayer films fabricated via sedimentation-sintering.

Carbohydrate polymers·2026
Same author

ROS-responsive self-immolative polymeric prodrug for nitrosative stress-mediated cancer therapy.

Journal of controlled release : official journal of the Controlled Release Society·2026

Related Experiment Video

Updated: Apr 20, 2026

Mammalian Cell Encapsulation in Alginate Beads Using a Simple Stirred Vessel
10:20

Mammalian Cell Encapsulation in Alginate Beads Using a Simple Stirred Vessel

Published on: June 29, 2017

21.0K

Nanocellulose-alginate hydrogel for cell encapsulation.

Minsung Park1, Dajung Lee1, Jinho Hyun2

  • 1Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul 151-921, Republic of Korea.

Carbohydrate Polymers
|December 3, 2014
PubMed
Summary
This summary is machine-generated.

TEMPO-oxidized bacterial cellulose (TOBC) and sodium alginate (SA) hydrogels enhance structural and mechanical properties for improved cell encapsulation. These TOBC/SA composites show promise for cell encapsulation engineering applications.

Keywords:
AlginateBacterial celluloseCell encapsulationTEMPO-oxidization

More Related Videos

Alginate Encapsulation of Pluripotent Stem Cells Using a Co-axial Nozzle
07:13

Alginate Encapsulation of Pluripotent Stem Cells Using a Co-axial Nozzle

Published on: July 2, 2015

13.6K
Encapsulation Thermogenic Preadipocytes for Transplantation into Adipose Tissue Depots
08:30

Encapsulation Thermogenic Preadipocytes for Transplantation into Adipose Tissue Depots

Published on: June 2, 2015

9.9K

Related Experiment Videos

Last Updated: Apr 20, 2026

Mammalian Cell Encapsulation in Alginate Beads Using a Simple Stirred Vessel
10:20

Mammalian Cell Encapsulation in Alginate Beads Using a Simple Stirred Vessel

Published on: June 29, 2017

21.0K
Alginate Encapsulation of Pluripotent Stem Cells Using a Co-axial Nozzle
07:13

Alginate Encapsulation of Pluripotent Stem Cells Using a Co-axial Nozzle

Published on: July 2, 2015

13.6K
Encapsulation Thermogenic Preadipocytes for Transplantation into Adipose Tissue Depots
08:30

Encapsulation Thermogenic Preadipocytes for Transplantation into Adipose Tissue Depots

Published on: June 2, 2015

9.9K

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Tissue Engineering

Background:

  • Hydrogels are crucial for cell encapsulation but often lack sufficient mechanical and chemical stability.
  • Bacterial cellulose (BC) possesses excellent mechanical properties but requires modification for better integration into hydrogel systems.

Purpose of the Study:

  • To develop novel TEMPO-oxidized bacterial cellulose (TOBC)-sodium alginate (SA) composite hydrogels.
  • To enhance the structural, mechanical, and chemical stability of hydrogels for improved cell encapsulation.
  • To evaluate the suitability of TOBC/SA composites for cell encapsulation engineering.

Main Methods:

  • TEMPO-oxidized bacterial cellulose (TOBC) fibers were synthesized using a TEMPO/NaBr/NaClO system.
  • TOBC fibers were combined with sodium alginate (SA) and cross-linked using Ca(2+) ions.
  • Compression strength and chemical stability of the composite hydrogels were assessed.
  • Cell viability within the TOBC/SA hydrogel composites was investigated.

Main Results:

  • The TOBC/SA composite hydrogels exhibited significantly increased compression strength and chemical stability compared to pure SA hydrogels.
  • TOBC incorporation effectively enhanced the structural integrity and mechanical robustness of the hydrogel matrix.
  • Successful encapsulation of cells within the TOBC/SA composites was achieved.
  • High cell viability was maintained within the engineered hydrogel environment.

Conclusions:

  • TEMPO-oxidized bacterial cellulose (TOBC) is an effective component for reinforcing sodium alginate (SA) hydrogels.
  • The TOBC/SA composite hydrogels offer superior mechanical and chemical stability for cell encapsulation.
  • These enhanced hydrogel composites represent a promising platform for advanced cell encapsulation engineering.