Mechanisms for chromosome segregation
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Updated: Apr 20, 2026

Live Cell Imaging of Chromosome Segregation During Mitosis
Published on: March 14, 2018
Jean-Yves Bouet1, Mathieu Stouf, Elise Lebailly
1Laboratoire de Microbiologie et de Génétique Moléculaires, CNRS, F-31000 Toulouse, France
Abstract:
Bacteria face the problem of segregating their gigantic chromosomes without a segregation period restricted in time and space, as Eukaryotes do. Segregation thus involves multiple activities, general or specific of a chromosome region and differentially controlled. Recent advances show that these various mechanisms conform to a “pair and release” rule, which appears as a general rule in DNA segregation. We describe the latest advances in segregation of bacterial chromosomes with emphasis on the different pair and release mechanisms.
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