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Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
Published on: February 23, 2024
Increased wound pH as an indicator of local wound infection in second degree burns
Sayaka Ono1, Ryutro Imai1, Yukiko Ida1
1Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, Japan.
Insights
Monitoring wound pH in burn patients can help detect infections early. Consecutive pH measurements of exudates are a simple, immediate indicator for treating second-degree burns and preventing complications.
Area of Science:
- Wound healing research
- Clinical microbiology
- Biomedical engineering
Background:
- Wound pH significantly impacts healing processes.
- Healthy skin surface pH ranges from 4.2 to 5.6.
- Epithelialization is associated with decreasing skin surface pH.
Purpose of the Study:
- To investigate the role of wound exudate pH in second-degree burn infections.
- To determine if pH measurements can aid in early infection detection.
Main Methods:
- pH of exudates from 26 second-degree burn cases were measured.
- Cases were monitored for local burn wound infection.
- Causative organisms (Staphylococcus aureus, Staphylococcus epidermidis) were identified in infected cases.
Main Results:
- Measured pH values ranged from 5.0 to 10.0.
- No initial pH differences were observed between infected and non-infected wounds.
- In infected cases, pH elevation preceded clinical signs of infection.
Conclusions:
- Consecutive pH measurement of burn wound exudates is a valuable tool for early detection of local infection.
- This method offers immediate results and is clinically beneficial for managing second-degree burns.
Abstract:
Wound pH affects a number of important factors in wound healing. It is known that the pH of the skin surface of healthy adults and children is 4.2-5.6 and that it decreases with the lapse of epithelialization. We measured the pH of the exudates from second degree burns in 26 cases. Among these, local burn wound infection developed in 6 cases. The causative organisms were Staphylococcus aureus in 2 cases and Staphylococcus epidermidis in 4 cases. The maximum pH value measured was 10.0 and the minimum was 5.0 for all samples. There were no differences in the initial measurements of pH between the non-infected cases and the local-infected cases. In cases of local infection, the pH rose prior to the onset of clinical signs of local burn infection. By consecutive measurement of pH, early detection of local wound infection can be achieved and this is very beneficial in clinical practice. Moreover, measurement is very easy and results are available immediately. In conclusion, consecutive pH measurement of exudates is considered to be a useful indicator in the treatment of second degree burns.
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