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Fluid Mosaic Model

Fluid Mosaic Model

Scientists identified the plasma membrane in the 1890s and its principal chemical components (lipids and proteins) by 1915. The model for plasma membrane structure, proposed in 1935 by Hugh Davson and James Danielli, was the first model to be widely accepted in the scientific community. The model was based on the plasma membrane's "railroad track" appearance in early electron micrographs. Davson and Danielli theorized that the plasma membrane's structure resembled a sandwich...

The Fluid Mosaic Model

The Fluid Mosaic Model

The fluid mosaic model was first proposed as a visual representation of research observations. The model comprises the composition and dynamics of membranes and serves as a foundation for future membrane-related studies. The model depicts the structure of the plasma membrane with a variety of components, which include phospholipids, proteins, and carbohydrates. These integral molecules are loosely bound, defining the cell’s border and providing fluidity for optimal function.

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Updated: Apr 20, 2026

Formation of Biomembrane Microarrays with a Squeegee-based Assembly Method

Formation of Biomembrane Microarrays with a Squeegee-based Assembly Method

Published on: May 8, 2014

Mixed mosaic membranes prepared by layer-by-layer assembly for ionic separations.

Sahadevan Rajesh¹, Yu Yan, Hsueh-Chia Chang

¹Department of Chemical and Biomolecular Engineering and ‡Department of Chemistry and Biochemistry, University of Notre Dame , Notre Dame, Indiana 46556-5637, United States.

|December 4, 2014

Summary

This summary is machine-generated.

Charge mosaic membranes selectively separate salts from neutral solutes using a novel layer-by-layer assembly. These membranes exhibit enhanced ion permeability, enabling efficient ionic separations without violating electroneutrality.

Keywords:

charge mosaic membranes composite membranes ion permeation layer-by-layer assembly nanotubes

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Layer-by-layer Synthesis and Transfer of Freestanding Conjugated Microporous Polymer Nanomembranes

Layer-by-layer Synthesis and Transfer of Freestanding Conjugated Microporous Polymer Nanomembranes

Published on: December 15, 2015

Area of Science:

Materials Science
Separation Science
Nanotechnology

Background:

Charge mosaic membranes possess distinct cationic and anionic domains for selective separation.
Existing methods for creating these membranes can be complex.

Purpose of the Study:

To develop facile layer-by-layer assembly methods for generating charge mosaic membranes.
To investigate the transport properties of these novel membranes.

Main Methods:

Layer-by-layer assembly of polymeric nanotubes (polyethylenimine and poly(styrenesulfonate)) on sacrificial templates.
Deposition of nanotubes onto porous supports to create mixed mosaic membranes.
Characterization using scanning electron microscopy and transport experiments (hydraulic permeability, solute rejection).

Main Results:

Vertically aligned, non-overlapping nanotubes spanning membrane thickness were achieved.
Hydraulic permeability of 8 L m(-2) h(-1) bar(-1) in piezodialysis.
Mixed mosaic membranes showed higher permeability to ionic solutes (NaCl) than neutral solutes, with negative rejection observed.

Conclusions:

The facile layer-by-layer assembly method successfully produced functional charge mosaic membranes.
The unique nanostructure facilitates selective ion permeation while maintaining electroneutrality.
These membranes show promise for advanced ionic separation applications.