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Injectable tissue-engineered soft tissue for tissue augmentation.

Sung-Mi Rhee1, Hi-Jin You1, Seung-Kyu Han1

  • 1Department of Plastic Surgery, Korea University College of Medicine, Seoul, Korea.

Journal of Korean Medical Science
|December 5, 2014
PubMed
Summary
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Injectable tissue-engineered soft tissue, combining hyaluronic acid fillers with living human cells, offers an advanced solution for soft tissue augmentation. This innovative approach provides advantages over traditional methods for treating wrinkles and defects.

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Plastic Surgery

Background:

  • Soft tissue augmentation addresses wrinkles and defects using various materials like autografts, allografts, synthetics, and fillers.
  • Traditional methods have limitations, prompting the exploration of advanced tissue engineering solutions.

Purpose of the Study:

  • To review the emerging field of injectable tissue-engineered soft tissue for augmentation.
  • To highlight the composition and clinical application of novel regenerative fillers.

Main Methods:

  • Review of existing literature on soft tissue augmentation materials and techniques.
  • Focus on injectable tissue-engineered soft tissue utilizing hyaluronic acid and living human mesenchymal cells.

Main Results:

Keywords:
Cell TherapySoft TissueTissue Engineering

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  • Injectable tissue-engineered soft tissue, incorporating hyaluronic acid and mesenchymal cells (fibroblasts, adipose-derived stromal vascular fraction), is now clinically applicable.
  • This advanced filler offers potential advantages over conventional augmentation methods.

Conclusions:

  • Injectable tissue-engineered soft tissue represents a significant advancement in regenerative medicine for soft tissue augmentation.
  • The use of living cells within fillers provides a promising new avenue for treating soft tissue defects and wrinkles.