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The effects of bronchiectasis on asthma exacerbation
Hye Ran Kang1, Gyu-Sik Choi1, Sun Jin Park1
1Division of Pulmonology and Allergy, Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine, Seoul, Korea.
Tuberculosis and Respiratory Diseases
|December 5, 2014
Summary
Patients with both bronchiectasis and asthma experience more frequent asthma exacerbations. This comorbidity is linked to increased steroid use and emergency room visits, indicating difficult asthma control.
Area of Science:
- Pulmonology
- Respiratory Medicine
Background:
- Bronchiectasis and asthma are distinct respiratory conditions.
- A subset of patients presents with both bronchiectasis and asthma.
- Research on the impact of bronchiectasis on asthma exacerbations is limited.
Purpose of the Study:
- To investigate the effect of bronchiectasis on the exacerbation of asthma.
Main Methods:
- A cohort of 2,270 asthma patients was analyzed.
- Fifty patients with co-existing bronchiectasis and asthma were identified.
- Age- and sex-matched controls (n=50) with asthma but without bronchiectasis were selected.
Main Results:
- Patients with both bronchiectasis and asthma exhibited a significantly higher annual incidence of asthma exacerbation (1.08 vs. 0.35, p=0.004).
- The prevalence of steroid use (0.9 vs. 0.26, p=0.006) and emergency room visits (0.46 vs. 0.02, p=0.001) were also elevated in the bronchiectasis-asthma group.
- Bronchiectasis was present in 2.2% of the asthma patient cohort.
Conclusions:
- Bronchiectasis is associated with challenging asthma control.
- The presence of bronchiectasis exacerbates asthma outcomes.
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