Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

16
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
16
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.8K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.8K
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

20
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
20
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.8K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.8K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

5.0K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
5.0K
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

238
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
238

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phylogeny, phylogeography, and conservation of a rediscovered gecko from the Galápagos Islands.

PloS one·2025
Same author

Dengue Prediction in Latin America Using Machine Learning and the One Health Perspective: A Literature Review.

Tropical medicine and infectious disease·2022
Same author

Emotional intelligence and academic motivation in primary school students.

Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS·2022
Same author

Increased serum ferritin and interleukin-18 levels in children with dengue.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]·2019
Same author

Oropouche Virus: what is it and how it is transmitted?

Investigacion clinica·2018
Same author

Gefitinib and pyrrolidine dithiocarbamate decrease viral replication and cytokine production in dengue virus infected human monocyte cultures.

Life sciences·2017

Related Experiment Video

Updated: Apr 20, 2026

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.9K

[Allergic rhinitis in asthmatic patients].

Paola Reyes1, Yraima Larreal, Julia Arias

  • 1Servicio de Pediatría, Hospital General del Sur Dr. Pedro Iturbe, Maracaibo, Estado Zulia, Venezuela. yraimalarreal@yahoo.com.

Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|December 5, 2014
PubMed
Summary

Allergic rhinitis affects over 90% of pediatric asthma patients, often presenting with nasal symptoms and elevated IgE levels, indicating an allergic inflammatory response. This highlights the critical link between allergic rhinitis and asthma management in children.

Keywords:
ARIAAllergic rinitisAsthmaEosinophiliaIgE

More Related Videos

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

10.6K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.2K

Related Experiment Videos

Last Updated: Apr 20, 2026

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.9K
A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

10.6K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.2K

Area of Science:

  • Pediatric Allergy and Immunology
  • Respiratory Medicine
  • Clinical Diagnostics

Context:

  • Allergic rhinitis and bronchial asthma are common chronic inflammatory airway diseases.
  • A significant correlation exists between these two conditions, ranging from 28-78%.

Purpose:

  • To determine the prevalence and classification of allergic rhinitis in asthmatic children using the ARIA guidelines.
  • To assess total serum IgE levels and the presence of nasal and blood eosinophilia in this cohort.

Summary:

  • A study of 60 asthmatic children (ages 7-14) found a 93.3% prevalence of allergic rhinitis.
  • Common symptoms included allergic shiners and watery nasal discharge; sleep disturbances affected quality of life.
  • Laboratory findings revealed elevated eosinophils (85.7%) and total serum IgE (75%) in most patients, with nasal eosinophilia in 61.9%.

Impact:

  • This research underscores the high comorbidity of allergic rhinitis in pediatric asthma.
  • Findings confirm an IgE-mediated inflammatory process, crucial for guiding integrated treatment strategies.
  • Early diagnosis and management of allergic rhinitis can potentially improve asthma control and quality of life in affected children.