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Updated: Apr 20, 2026

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Is nutrition important to postpone frailty?

Eirini Kelaiditi1, Sophie Guyonnet, Matteo Cesari

  • 1aGérontopôle, Centre Hospitalier Universitaire de Toulouse bINSERM UMR 1027 cUniversité de Toulouse III-Paul Sabatier, Toulouse, France.

Current Opinion in Clinical Nutrition and Metabolic Care
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Current research on nutrition and frailty prevention is limited. More long-term, high-powered studies are needed to confirm nutrition

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Area of Science:

  • Gerontology
  • Nutritional Science
  • Public Health

Background:

  • Frailty is a growing concern in aging populations.
  • Understanding modifiable factors like nutrition is crucial for healthy aging.

Purpose of the Study:

  • To systematically review recent literature on nutrition's role in postponing frailty.
  • To identify gaps in current research.

Main Methods:

  • Systematic review of literature published within the past 12 months.
  • Analysis of nine identified studies, predominantly cross-sectional.
  • Inclusion of one pilot randomized controlled trial.

Main Results:

  • Limited recent evidence explores the nutrition-frailty relationship.
  • Existing studies show high variability in methods, hindering comparisons.
  • A single pilot trial had insufficient power and short follow-up.

Conclusions:

  • High-quality, long-term randomized controlled trials are essential.
  • Further research should investigate nutrition's efficacy in frailty postponement.
  • Combined interventions including nutrition warrant investigation.