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Updated: Apr 19, 2026

An In Vitro Dissolution Determination of Multi-Index Components in Tibetan Medicine Rhodiola Granules
Published on: November 4, 2022
[Analysis of dissolution characteristics and content of metal elements in Scutellaria baicalensis]
Abstract:
ICP-OES analytical technique was used to determine the contents of Ca, Mg, Cu, Zn, Fe and Mn in S. baicalensis from different origins, and the dissolution characteristics and the contents of 6 elements were analyzed. There were significant differences in the contents among the prepared medical materials (p < 0.05) and their water extraction also differed significantly. The results showed that there was no relationship on the contents of the 6 elements between in the prepared medical materials and in their water extraction In the prepared medical materials, the contents of the elements were characterized as Mg>Ca>Fe>Mn>Zn>Cu, and the contents in the water extraction was rated from high to low as Mg, Ca, Mn, Zn, Fe and Cu. Most of the measured samples demonstrated lower Ca/Mg, higher Fe/Mn and lower Cu/Zn values, and these ratios were in relation to some efficacy of S. baicalensis, such as anti-hypertensive, anti-tumor activities. The results will provide a scientific basis for further enriching and developing the multi-index system for the quality evaluation.
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