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Updated: Apr 19, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Flow Augmentation in Acute Ischemic Stroke
Golnaz Yadollahikhales1, Afshin Borhani-Haghighi2, Mohammad Torabi-Nami3
1Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Fars, Iran.
Abstract:
There is an urgent need for additional therapeutic options for acute ischemic stroke considering the major pitfalls of the options available. Herein, we briefly review the role of cerebral blood flow, collaterals, vasoreactivity, and reperfusion injury in acute ischemic stroke. Then, we reviewed pharmacological and interventional measures such as volume expansion and induced hypertension, intra-aortic balloon counterpulsation, partial aortic occlusion, extracranial-intracranial carotid bypass surgery, sphenopalatine ganglion stimulation, and transcranial laser therapy with regard to their effects on flow augmentation and neuroprotection.
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