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Major Cognitive Changes and Micrographia following Globus Pallidus Infarct

Sarah Nelson1, Hassanain Toma2, Haley LaMonica3

  • 1Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.

Case Reports in Neurological Medicine
|December 6, 2014
PubMed

Insights

Globus pallidus (GP) infarcts can cause significant cognitive problems, not just motor deficits. This case highlights the potential need for neuropsychological testing after GP strokes.

Area of Science:

  • Neuroscience
  • Neurology
  • Cognitive Science

Background:

  • Globus pallidus (GP) lesions are primarily associated with motor deficits.
  • The link between GP lesions and cognitive impairment is less established.
  • Micrographia is a recognized but less localized neurological finding.

Purpose of the Study:

  • To report a case of a patient with globus pallidus infarct.
  • To investigate the association between GP lesions and cognitive deficits.
  • To explore the occurrence of micrographia in relation to GP lesions.

Main Methods:

  • Case report of a 45-year-old male with a globus pallidus infarct.
  • Clinical observation of motor, cognitive, and psychological changes post-stroke.
  • Documentation of micrographia.

Main Results:

  • The patient developed substantial cognitive problems following a GP infarct.
  • Micrographia was observed in the patient.
  • Formal neuropsychological testing was limited due to patient follow-up issues.

Conclusions:

  • This case suggests a potential link between globus pallidus lesions and significant cognitive deficits.
  • The findings support the localization of micrographia in relation to GP lesions.
  • Neuropsychological evaluation may be warranted after globus pallidus strokes.

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