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Randomised trial of text messaging on adherence to cardiovascular preventive treatment (INTERACT trial)

David S Wald1, Jonathan P Bestwick1, Lewis Raiman1

  • 1Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, United Kingdom.

Plos One
|December 6, 2014
PubMed

Insights

Text messages significantly improved medication adherence for patients taking cardiovascular disease preventive treatments. This simple intervention helped more patients stay on their prescribed blood pressure and lipid-lowering drugs.

Area of Science:

  • Cardiology
  • Digital Health
  • Public Health

Background:

  • Medication non-adherence affects one-third of patients prescribed cardiovascular preventive drugs.
  • Poor adherence to blood pressure and lipid-lowering medications increases risks for coronary heart disease and stroke.

Purpose of the Study:

  • To evaluate the effectiveness of text messaging in improving medication adherence for cardiovascular disease prevention.

Main Methods:

  • A randomized trial involving 303 patients prescribed blood pressure and/or lipid-lowering medications.
  • Patients were assigned to receive daily, alternate-day, and then weekly text messages for 6 months or a control group.
  • Medication adherence and reasons for non-adherence were assessed via patient responses to automated texts.

Main Results:

  • Medication adherence improved in the text message group (9% non-adherence) compared to the control group (25% non-adherence).
  • Text messages reminded 65% of patients to take their medication, leading 13% to resume treatment after concerns.

Conclusions:

  • Text messaging is an effective strategy to enhance medication adherence in patients on cardiovascular preventive treatment.
  • This digital health intervention offers a scalable solution to improve cardiovascular disease prevention outcomes.
Abstract

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