Poor responders in IVF: an update in therapy.

Area of Science:

• Reproductive Medicine
• Infertility Treatment
• Assisted Reproductive Technology

Background:

• Assisted reproduction techniques are common infertility treatments.
• Managing poor responder patients remains a significant challenge in reproductive medicine.
• A lack of a unified definition complicates the management of poor responders.

Purpose of the Study:

• To review and compare studies on poor responder patients in assisted reproduction.
• To examine existing therapies for patients with poor ovarian response.
• To highlight the need for standardized definitions and treatments.

Main Methods:

• Conducted an online literature search of MEDLINE/PUBMED.
• Identified studies focusing on pharmacological treatments for poor responders.
• Analyzed various therapeutic approaches evaluated in existing research.

Main Results:

• Numerous therapies for poor responders have been studied over the years.
• The primary issue remains the broad and ill-defined concept of 'poor responder'.
• Existing studies show diverse therapeutic strategies for ovarian stimulation non-responders.

Conclusions:

• Management of poor responder patients is complex and lacks standardized treatment protocols.
• Identifying clear diagnostic and therapeutic targets is crucial.
• Further in-depth research is necessary to standardize approaches for poor responders.