Related Experiment Video
Updated: Apr 19, 2026

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Incident depression increases medical utilization in Medicaid patients with hypertension
Ian Michael Breunig1, Fadia T Shaya, Justin Tevie
1Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, 220 Arch St, 12th Floor, Baltimore, MD 21201, USA.
Insights
Newly diagnosed depression in hypertension patients increased overall medical visits, but not specifically for cardiovascular issues. This suggests depression impacts healthcare use differently than previously assumed for hypertension management.
Area of Science:
- Cardiology
- Psychiatry
- Health Services Research
Background:
- Hypertension is a major cardiovascular disease risk factor.
- Depression disproportionately affects hypertensive patients.
- Limited research exists on outcomes for hypertensive patients with newly diagnosed depression.
Purpose of the Study:
- To investigate if incident depression exacerbates hypertensive disease.
- To determine if depression leads to increased medical service utilization in hypertensive patients.
Main Methods:
- Utilized Maryland Medicaid claims data (2005-2010) for hypertensive patients.
- Compared annualized medical utilization post-incident depression to a matched cohort without depression.
- Employed multivariate regression to control for medication, adherence, and comorbidity changes.
Main Results:
- Medical utilization increased following incident depression.
- Increased encounters were primarily for non-acute medical care.
- No significant rise in cardiovascular or hypertension-specific encounters was observed.
Conclusions:
- Incident depression in hypertensive patients is associated with increased overall medical utilization.
- The increase in utilization is not specifically linked to cardiovascular or hypertension-related conditions.
- Findings inform future research on long-term outcomes in comorbid hypertension and depression.
Unlabelled:
Hypertension is an important risk factor for cardiovascular disease and occurs disproportionately among patients with depression. Few studies have rigorously examined outcomes specifically among hypertensive patients with newly diagnosed comorbid depression.
Aim:
We hypothesized that incident depression would exacerbate hypertensive disease and that this would be evident through greater utilization of medical services than would otherwise occur in the absence of depression.
Methods:
Claims data for hypertensive patients enrolled in Maryland Medicaid (2005-2010) were used to estimate the change in annualized utilization following incident depression, compared to a matched cohort of hypertensive patients never diagnosed with depression. Multivariate regression was used to adjust for changes in antihypertensive medications, adherence and comorbidity that followed depression onset.
Results:
While medical utilization increased after incident depression, additional encounters tended to be for nonacute medical care and there was no significant increase in encounters specifically for cardiovascular or hypertension-related conditions.
Discussion:
The results contribute to the discussion on the relationship between depression and cardiovascular disease and will inform future studies that aim to look at longer term outcomes in patients with hypertension.
Related Concept Videos
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Acute Coronary Syndrome IV: Interprofessional Care
Hypertension V: Nursing Management
Hypertension I: Introduction
Drug Toxicity: Risk factors
Hypertension III: Clinical Manifestations and Diagnostic Studies
