Related Experiment Video
Updated: Apr 19, 2026

In Vivo Optical Imaging of Brain Tumors and Arthritis Using Fluorescent SapC-DOPS Nanovesicles
Published on: May 2, 2014
Novel imaging modalities in spondyloarthritis
Lennart Jans1, Jacob L Jaremko2, Gurjit S Kaeley3
1Department of Radiology, Faculty of Medicine, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium.
Magnetic resonance imaging (MRI) and ultrasound offer advanced methods for diagnosing and monitoring spondyloarthritis (SpA). This review details their use in clinical practice, focusing on evolving definitions and interpretation of imaging findings.
Area of Science:
- Rheumatology and Musculoskeletal Imaging
- Diagnostic Imaging in Inflammatory Diseases
Background:
- Spondyloarthritis (SpA) diagnosis and monitoring benefit from advanced imaging techniques.
- Magnetic resonance imaging (MRI) and ultrasound (US) are key modalities for evaluating axial and peripheral SpA.
- Evolving definitions of imaging findings necessitate updated guidance for clinicians.
Purpose of the Study:
- To review the role, sensitivity, and specificity of MRI and ultrasound in diagnosing and monitoring SpA.
- To discuss the evolving definition of a 'positive MRI' for sacroiliac joints and spine.
- To provide guidance on the practical application and interpretation of these imaging modalities in daily practice.
Main Methods:
- Review of current literature on MRI and ultrasound in spondyloarthritis.
- Discussion of diagnostic criteria and interpretation of imaging findings.
- Analysis of the utility of imaging as a clinical and outcome measure.
Main Results:
- MRI and ultrasound demonstrate significant roles in detecting and monitoring inflammatory changes in SpA.
- The interpretation of 'positive MRI' findings, particularly in the sacroiliac joints and spine, is dynamic.
- Ultrasound is valuable for assessing peripheral manifestations including enthesitis and synovitis.
Conclusions:
- MRI and ultrasound are crucial tools for the comprehensive assessment of spondyloarthritis.
- Understanding evolving imaging definitions and differential diagnoses is essential for accurate interpretation.
- This review offers practical guidance for integrating advanced imaging into routine SpA management.
Related Concept Videos
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Imaging Studies VII: Vascular Imaging
Imaging Studies III: Computed Tomography
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies for Cardiovascular System IV: CMRI

