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[Kidney diseases in elderly patients]
Dirk Bareiss1, Michael Dickenmann1, Felix Burkhalter1
1Transplantationsimmunologie und Nephrologie, Universitätsspital Basel.
Insights
Chronic kidney disease (CKD) is more common in older adults due to increased risk factors like hypertension and diabetes. Early diagnosis and personalized treatment decisions are crucial for managing CKD progression in the elderly.
Area of Science:
- Nephrology
- Geriatrics
- Internal Medicine
Context:
- Chronic kidney disease (CKD) prevalence significantly rises with aging.
- Hypertension, diabetes, and obesity are key risk factors contributing to CKD in older populations.
- Physiological kidney aging leads to functional impairments and increased susceptibility to electrolyte disorders and perfusion deficits.
Purpose:
- To highlight the importance of early CKD diagnosis in the elderly.
- To emphasize the role of aging kidneys and associated risk factors in CKD development.
- To guide treatment decisions for end-stage renal disease (ESRD) in older patients.
Summary:
- CKD incidence escalates with age, driven by comorbidities like hypertension and diabetes.
- Kidney aging contributes to functional decline, electrolyte imbalances, and perfusion issues, often exacerbated by medications.
- Treatment decisions for ESRD in the elderly should prioritize patient preferences, comorbidities, and quality of life over chronological age.
Impact:
- Facilitates timely intervention to slow CKD progression in geriatric populations.
- Informs healthcare providers about age-related renal changes and risk factors.
- Promotes individualized care plans for elderly CKD patients, ensuring better quality of life and treatment outcomes.
Abstract:
The prevalence of CKD increases with old age. The increase of risk factors for the development of CKD such as hypertension, diabetes and adipositas is essentially responsible for this. For the treating physician it is therefore important to diagnose CKD early to slow its progression. Physiological aging of the kidney is responsible for the development of functional impairments in the elderly. Electrolyte disorders and hemodynamically caused perfusion deficits are more frequent in old age and are often caused by medication. If kidney replacement therapy in end stage renal disease in the elderly is initiated or not should not depend on age but should consider patient preference, comorbidities and quality of life, which together are ideally assessed early.
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