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A maternal functioning adrenocortical adenoma causing fetal female pseudohermaphroditism
M Miyata1, M Nishihara, S Tokunaka
1Department of Urology, Asahikawa Medical College, Japan.
The Journal of Urology
|September 1, 1989
Summary
Maternal adrenal tumors causing fetal virilization are exceptionally rare. This case highlights an adrenocortical tumor with Cushing
Area of Science:
- Endocrinology
- Reproductive Medicine
- Oncology
Background:
- Maternal adrenal tumors are rare causes of endocrine disruption.
- Cushing's syndrome in pregnancy can lead to significant maternal and fetal complications.
Observation:
- A case of a pregnant patient with an adrenocortical tumor presenting with Cushing's syndrome.
- The tumor led to virilization of the fetus.
Findings:
- Demonstration of a rare instance of fetal virilization due to maternal adrenocortical tumor.
- Correlation between maternal Cushing's syndrome and fetal androgen excess.
Implications:
- Underscores the importance of recognizing rare endocrine disorders during pregnancy.
- Informs clinical management strategies for pregnant patients with adrenal masses and suspected Cushing's syndrome.
- Highlights potential risks of fetal virilization in such cases.