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Clinical Practice Protocol of Creative Music Therapy for Preterm Infants and Their Parents in the Neonatal Intensive Care Unit
Published on: January 7, 2020
Music and 25% glucose pain relief for the premature infant: a randomized clinical trial
Maria Vera Lúcia Moreira Leitão Cardoso1, Leiliane Martins Farias2, Gleicia Martins de Melo1
1Departamento de Enfermagem, Universidade Federal do Ceará, Fortaleza, CE, Brazil.
Insights
Music and 25% glucose interventions did not significantly alter pain scores in premature infants. However, neonatal variables like head circumference and Apgar scores were associated with pain levels.
Area of Science:
- Neonatal care
- Pain management
Background:
- Premature infants experience significant pain during medical procedures.
- Assessing and managing pain in neonates is crucial for their well-being.
- Interventions like music and glucose are explored to alleviate procedural pain.
Purpose of the Study:
- To evaluate the effectiveness of music and 25% glucose interventions on pain scores in premature infants during arterial puncture.
- To identify neonatal and therapeutic variables associated with pain in this population.
Main Methods:
- A randomized clinical trial involving 80 premature infants.
- Three groups: music intervention, music plus 25% glucose, and 25% glucose alone.
- Pain was assessed using the Premature Infant Pain Profile (PIPP) scores, with infants videotaped during the procedure.
Main Results:
- No statistically significant difference in pain scores was found between the intervention groups.
- 60% of infants experienced moderate to severe pain.
- Significant associations were observed between pain scores and variables such as head/chest circumference, Apgar scores, corrected gestational age, oxygen therapy, and birth weight, depending on the group.
Conclusions:
- Neonatal variables, rather than the tested interventions, appear to be significantly associated with pain experienced by premature infants during arterial puncture.
- Further research may be needed to identify more effective pain management strategies for this vulnerable population.
Objective:
To analyze the total Premature Infant Pain Profile scores of premature infants undergoing arterial puncture during music and 25% glucose interventions, and to assess their association with neonatal and therapeutic variables.
Method:
A randomized clinical trial with 80 premature infants; 24 in the Experimental Group 1 (music), 33 in the Experimental Group 2 (music and 25% glucose), 23 in the Positive Control Group (25% glucose). All premature infants were videotaped and a lullaby was played for ten minutes before puncture in Experimental Groups 1 and 2; 25% glucose administered in Experimental Group 2 and the Positive Control Group two minutes before puncture.
Results:
60.0% of premature infants had moderate or maximum pain; pain scores and intervention groups were not statistically significant. Statistically significant variables: Experimental Group 1: head and chest circumference, Apgar scores, corrected gestational age; Experimental Group 2: chest circumference, Apgar scores, oxygen therapy; Positive Control group: birth weight, head circumference.
Conclusion:
Neonatal variables are associated with pain in premature infants. Brazilian Registry of Clinical Trials: UTN: U1111-1123-4821.

