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Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Apr 19, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Published on: August 4, 2018

Scanning laser polarimetry in glaucoma.

Tanuj Dada¹, Reetika Sharma, Dewang Angmo

¹Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Instituteof Medical Sciences, New Delhi, India.

Indian Journal of Ophthalmology

|December 11, 2014

Summary

This summary is machine-generated.

Scanning laser polarimetry (SLP) offers a method for measuring retinal nerve fiber layer (RNFL) thickness, aiding in early glaucoma detection before significant vision loss occurs.

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Last Updated: Apr 19, 2026

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Published on: August 4, 2018

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Doppler Optical Coherence Tomography of Retinal Circulation

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Area of Science:

Ophthalmology
Medical Technology

Background:

Glaucoma is a progressive optic neuropathy characterized by optic nerve head and retinal nerve fiber layer (RNFL) changes.
Current gold standard, white-on-white perimetry, detects visual field defects only after substantial ganglion cell loss (up to 40%).
RNFL thickness measurement is crucial for earlier glaucoma diagnosis.

Purpose of the Study:

To review the published literature on the use of Scanning Laser Polarimetry (SLP) in glaucoma.
To elucidate the technological principles, recent developments, and the role of SLP in diagnosing and monitoring glaucomatous optic neuropathy.

Main Methods:

Literature review of published studies on SLP in glaucoma.
Evaluation of scientific evidence regarding SLP's efficacy.

Main Results:

SLP provides RNFL thickness measurements utilizing the birefringence of retinal ganglion cell axons.
The review synthesizes information on SLP's principles, advancements, and clinical application in glaucoma.

Conclusions:

RNFL thickness measurement, particularly via SLP, is a valuable adjunct for glaucoma evaluation.
SLP shows promise in the early diagnosis and monitoring of glaucomatous optic neuropathy.