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Updated: Apr 19, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Preoperative evaluation before MitraClip®: present and future perspective
Gemma Salerno1, Frank Patrick Schmidt, Maurizio Cappelli Bigazzi
1Department of Cardiology, Second University of Naples, Ospedale dei Colli, Naples, Italy.
Insights
Mitral regurgitation (MR) management includes medical, surgical, and percutaneous options. The MitraClip system offers a promising minimally invasive approach for severe MR, with growing evidence supporting a multiparametric patient selection strategy.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Mitral regurgitation (MR) is a prevalent heart valve disease globally.
- Current management involves medical therapy, surgery, and percutaneous interventions.
- Many patients are not referred for surgery due to comorbidities or high surgical risk.
Purpose of the Study:
- To review the current landscape of mitral regurgitation management.
- To highlight the growing importance of percutaneous mitral valve repair.
- To emphasize the potential of the MitraClip system for treating severe MR.
Main Methods:
- Review of current medical, surgical, and percutaneous treatment strategies for MR.
- Focus on the MitraClip system as a leading percutaneous approach.
- Discussion on patient selection criteria for MitraClip implantation.
Main Results:
- Percutaneous approaches, particularly MitraClip, are emerging as key treatments for severe MR.
- A significant proportion of eligible patients are not undergoing surgery.
- Echocardiography is standard for patient selection, but a multiparametric approach is gaining traction.
Conclusions:
- Percutaneous mitral valve repair offers a less invasive option for severe MR.
- The MitraClip system is a promising technology in this field.
- A comprehensive patient assessment, including functional status, may improve selection for percutaneous mitral valve repair.
Abstract:
Mitral regurgitation (MR) is the second most common heart valve disease worldwide. Currently, the management of MR is based on medical therapy (including biventricular pacing), surgery (mitral valve replacement or repair) and percutaneous therapy. However, in spite of guideline recommendations, 50% of individuals assessed in the Euro Heart Survey were not referred to surgical intervention due to comorbidities or real or perceived high risks for cardiac surgery; thus, in recent years, the focus of research has shifted to the development of percutaneous approaches to treat severe MR in order to restore valve function in a minimally invasive fashion. Among these techniques, the percutaneous mitral valve repair procedure using the MitraClip(®) system (Abbott Vascular, IL, USA) is one of the most promising. Usually, patient selection for MitraClip implantation is based on careful echocardiographic assessment of valve disease; however, although definitive data are lacking, evidence is mounting for a multiparametric approach including the evaluation of the functional status of patients.
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