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Perivalvular Complication in Infective Endocarditis: An Integrated Imaging Approach in the Diagnostic Workup
Chiara Sordelli1, Carlo Liguori2, Nunzia Fele1
1Department of Cardiology, Monaldi Hospital, Naples, Italy.
Insights
Infective endocarditis diagnosis relies on imaging. Transesophageal echocardiography (TEE) and cardiac CT are crucial for assessing cardiac complications in infective endocarditis (IE).
Area of Science:
- Cardiology
- Medical Imaging
- Infectious Diseases
Background:
- Infective endocarditis (IE) is a serious condition with significant morbidity and mortality.
- Current guidelines emphasize imaging for IE diagnosis, with echocardiography as the primary tool.
- Limitations in initial echocardiography may necessitate advanced imaging techniques.
Purpose of the Study:
- To review the role of cardiac imaging in evaluating infective endocarditis.
- To specifically assess the utility of transesophageal echocardiography (TEE) and cardiac computed tomography (CT) in diagnosing IE perivalvular complications.
Main Methods:
- Review of current literature and guidelines regarding cardiac imaging in IE.
- Focus on the diagnostic capabilities of transthoracic echocardiography (TTE), TEE, and cardiac CT.
- Evaluation of imaging for assessing IE lesions and associated cardiac complications.
Main Results:
- Echocardiography is the first-line diagnostic imaging modality for IE.
- Transesophageal echocardiography (TEE) is essential for inconclusive or suspected IE cases and for detailing complications.
- Cardiac CT and nuclear imaging aid in confirming diagnosis, characterizing lesions, and identifying cardiac complications.
Conclusions:
- Cardiac imaging, particularly TEE and cardiac CT, plays a vital role in the comprehensive evaluation of infective endocarditis.
- These advanced imaging modalities are crucial for diagnosing and managing IE-related perivalvular complications.
- Multimodality imaging approaches enhance diagnostic accuracy and patient management in IE.
Abstract:
Infective endocarditis (IE) is a rare disease, but its impact is significant as it affects 3-10/100,000 per year in the population. According to the current guidelines ESC 2023, the evidence of lesions characteristic of IE is a major diagnostic criterion. Echocardiography is the first-line imaging technique to diagnose IE and to assess the structural and functional damage of cardiac structures. Transesophageal echocardiography (TEE) is recommended in patients with an inconclusive or negative TTE, in patients with high suspicion of IE, as well as in patients with a positive TTE, to document local complications. Other imaging modalities, such as cardiac computed tomography and nuclear imaging, are needed to confirm or exclude the diagnosis of IE, to characterize the extent of the cardiac lesions, and to diagnose cardiac complications. The aim of this article was to review the potential role of cardiac imaging, especially of TEE and cardiac CT in evaluating IE perivalvular complications.
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