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Updated: Apr 19, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Development of scleroderma renal crisis in a patient with undiagnosed scleroderma]
Kristine Lindhard Madsen1, Alastair Hansen, Poul Halberg
1Nefrologisk Afdeling, Hillerød Hospital, Dyrehavevej 29, 4900 Hillerød. kristine.lindhard@gmail.com.
Abstract:
Less than 10% of the patients with systemic scleroderma develop renal crisis, i.e. acute renal failure and severe hypertension in most cases. Kidney biopsy shows hypertensive arteriolar changes. This complication was lethal until treatment with captopril was introduced in 1976. Since that time the survival of the patients has improved. If treatment is started early, further deteoriation of the kidney may be prevented.
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