Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Spongy Bone01:09

Spongy Bone

14.2K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
14.2K
Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity01:15

Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity

792
Deformation occurs in axial and transverse directions when an axial load is applied to a slender bar. This deformation impacts the cubic element within the bar, transforming it into either a rectangular parallelepiped or a rhombus, contingent on its orientation. This transformation process induces shearing strain. Axial loading elicits both shearing and normal strains. Applying an axial load instigates equal normal and shearing stresses on elements oriented at a 45° angle to the load axis.
792
Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

8.3K
Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts—...
8.3K
Elastin is Responsible for Tissue Elasticity01:12

Elastin is Responsible for Tissue Elasticity

3.5K
Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...
3.5K
Bending of Members Made of Several Materials01:11

Bending of Members Made of Several Materials

775
In analyzing a structural member composed of two different materials with identical cross-sectional areas, it is crucial to understand how their distinct elastic properties affect the member's response under load. The analysis involves assessing stress and strain distributions using the transformed section concept, which accounts for variations in material properties.
Hooke's Law determines stress in each material, stating that stress is proportional to strain but varies due to each material's...
775
The Bone Matrix01:18

The Bone Matrix

10.2K
Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
10.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of degenerative states of articular cartilage via sparse laser-based mid-infrared attenuated total reflectance spectroscopy.

Osteoarthritis and cartilage open·2026
Same author

Laser-irradiating infrared attenuated total reflection spectroscopy of articular cartilage: Potential and challenges for diagnosing osteoarthritis.

Osteoarthritis and cartilage open·2024
Same author

Infrared spectroscopy is suitable for objective assessment of articular cartilage health.

Osteoarthritis and cartilage open·2022
Same author

Prenatal murine skeletogenesis partially recovers from absent skeletal muscle as development progresses.

European cells & materials·2022
Same author

Phase-contrast enhanced synchrotron micro-tomography of human meniscus tissue.

Osteoarthritis and cartilage·2022
Same author

A practical guide for in situ mechanical testing of musculoskeletal tissues using synchrotron tomography.

Journal of the mechanical behavior of biomedical materials·2022

Related Experiment Video

Updated: Apr 19, 2026

Investigating Stress-relaxation and Failure Responses in the Trachea
08:07

Investigating Stress-relaxation and Failure Responses in the Trachea

Published on: October 18, 2022

2.3K

Relationships between tissue composition and viscoelastic properties in human trabecular bone.

X Ojanen1, H Isaksson2, J Töyräs3

  • 1Department of Applied Physics, University of Eastern Finland, Kuopio, Finland.

Journal of Biomechanics
|December 16, 2014
PubMed
Summary

Trabecular bone

Keywords:
AgingBone matrixFemoral neckNanoindentationRaman microspectroscopy

More Related Videos

Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography
07:57

Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography

Published on: May 10, 2022

2.8K
Biomechanical Characterization of Human Soft Tissues Using Indentation and Tensile Testing
07:07

Biomechanical Characterization of Human Soft Tissues Using Indentation and Tensile Testing

Published on: December 13, 2016

33.6K

Related Experiment Videos

Last Updated: Apr 19, 2026

Investigating Stress-relaxation and Failure Responses in the Trachea
08:07

Investigating Stress-relaxation and Failure Responses in the Trachea

Published on: October 18, 2022

2.3K
Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography
07:57

Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography

Published on: May 10, 2022

2.8K
Biomechanical Characterization of Human Soft Tissues Using Indentation and Tensile Testing
07:07

Biomechanical Characterization of Human Soft Tissues Using Indentation and Tensile Testing

Published on: December 13, 2016

33.6K

Area of Science:

  • Biomaterials Science
  • Bone Physiology
  • Tissue Engineering

Background:

  • Trabecular bone is metabolically active and sensitive to metabolic changes.
  • Its viscoelastic properties may change with age, but relationships with composition are unclear.

Purpose of the Study:

  • To investigate the associations between trabecular bone composition and viscoelastic properties.
  • To determine how these properties change with age.

Main Methods:

  • Trabecular bone samples from male cadavers (aged 17-82) were analyzed.
  • Raman microspectroscopy and nanoindentation were used to assess composition and viscoelasticity.

Main Results:

  • Viscoelastic creep parameters correlated significantly with mineral crystallinity.
  • Mineralization decreased and carbonate substitution increased with age.
  • Age did not significantly affect nanoindentation parameters.

Conclusions:

  • Trabecular bone's viscoelastic properties are linked to bone mineral characteristics.
  • This relationship appears independent of age.