Uremic neuropathy and treatment with renal transplantation

Uremic neuropathy is one of the most debilitating symptoms associated with end stage renal disease. Severity can range from mild weakness in the lower extremities to complete physical disability. The only potential cure for uremic neuropathy is renal transplantation. This article will review the literature and describe the clinical features, the etiology, and the treatment of uremic neuropathy. A case history will follow to illustrate the dramatic change in a patient who was referred to a North Carolina institution with severe uremic neuropathy for renal transplantation.