[Hereditary angioedema: treatment and educational therapeutic program]

Area of Science:

• Immunology
• Genetics
• Pharmacology

Context:

• Hereditary angioedema (HAE) is a rare genetic disorder characterized by unpredictable, severe, and potentially life-threatening acute attacks.
• Effective management of HAE requires a dual approach: immediate treatment of acute attacks and long-term strategies to prevent their recurrence.

Purpose:

• To outline the key objectives and strategies for managing Hereditary Angioedema (HAE).
• To emphasize the importance of timely intervention, patient self-administration, and prophylaxis in HAE care.
• To highlight the role of educational programs in empowering patients and their families.

Summary:

• Acute HAE attacks necessitate prompt treatment for optimal efficacy and patient safety, with self-administration being encouraged to enhance autonomy and reduce treatment delays.
• Long-term prophylaxis is crucial for minimizing the frequency of HAE attacks, thereby improving patients' overall quality of life and safety.
• Short-term prophylaxis is recommended before known HAE triggers, such as surgical or dental procedures, with established protocols like CREAK available.
• The HAE National Educational Therapeutic Program (Educreak) aims to equip patients and their support networks with the necessary skills for independent daily disease management.

Impact:

• Improved patient outcomes through timely and appropriate HAE treatment.
• Enhanced patient quality of life and safety by reducing the frequency and severity of acute attacks.
• Increased patient autonomy and self-management capabilities via education and self-administration training.