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A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury
Published on: June 20, 2017
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Mild traumatic brain injury: neurosensory effects
1Department of Otolaryngology, Miller School of Medicine, University of Miami, Miami, Florida, USA.
Current Opinion in Neurology
|December 16, 2014
Summary
Recent advances in mild traumatic brain injury (mTBI) diagnosis and treatment are reviewed. Objective diagnosis of neurosensory sequelae like dizziness shows promise, while further research is needed for pharmaceutical interventions.
Area of Science:
- Neuroscience
- Public Health
- Clinical Medicine
Background:
- Mild traumatic brain injury (mTBI) presents complex diagnostic challenges.
- Neurosensory sequelae, including headache, cognitive effects, and fatigue, are difficult to quantify objectively.
- Dizziness is a common and objectively measurable symptom in mTBI patients.
Purpose of the Study:
- To review recent advancements in diagnosing and treating mild traumatic brain injury.
- To focus on the neurosensory consequences of mTBI.
- To highlight the importance of understanding neurosensory manifestations for accurate prognosis.
Main Methods:
- Literature review of recent studies (last 18 months) on mTBI diagnosis and treatment.
- Analysis of diagnostic challenges for subjective and objective neurosensory sequelae.
- Evaluation of current and emerging treatment strategies.
Main Results:
- Significant progress in mTBI diagnosis, particularly for objectively measurable symptoms like dizziness.
- Challenges remain in accurately measuring subjective symptoms such as headache, cognitive deficits, and fatigue.
- Limited pharmaceutical advancements, with one reported countermeasure requiring further development.
- Therapeutic interventions remain the primary treatment modality, necessitating continued support and research.
Conclusions:
- Mild traumatic brain injury is an escalating public health concern.
- Clinicians must be knowledgeable about neurosensory manifestations for effective diagnosis and treatment.
- Accurate diagnosis and prognosis are crucial for patient and family care.

