Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antiretroviral therapy.

B H Thiers1

  • 1Department of Dermatology, Medical University of South Carolina, Charleston 29425-2215.

Journal of the American Academy of Dermatology
|September 1, 1989
PubMed
Summary
This summary is machine-generated.

Understanding the human immunodeficiency virus type 1 (HIV-1) replication cycle is key to developing effective treatments. Each stage presents potential targets for antiviral therapies, though challenges remain for a universal vaccine.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Varicella-zoster and herpes simplex virus reactivation post-COVID-19 vaccination: a review of 40 cases in an International Dermatology Registry.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same author

Cutaneous T-cell lymphoma.

Journal of the European Academy of Dermatology and Venereology : JEADV·2003
Same author

Systemic Weber-Christian disease.

Journal of cutaneous medicine and surgery·2001
Same author

Topical tacrolimus: treatment failure in a patient with alopecia areata.

Archives of dermatology·2000
Same author

Dermatology therapy update.

The Medical clinics of North America·1999
Same author

Psoriasis therapy update.

The Western journal of medicine·1998
Same journal

Comparative Alopecia Outcomes After Copper and Hormonal Intrauterine Device Placement: A TriNetX Database Retrospective Cohort Study.

Journal of the American Academy of Dermatology·2026
Same journal

Uncovering a Dual Th17/Type 2 Transcriptomic Endotype in Psoriasis.

Journal of the American Academy of Dermatology·2026
Same journal

Dermatologic conditions associated with HIV among US adults across different racial and ethnic groups: A retrospective cohort study using TriNetX.

Journal of the American Academy of Dermatology·2026
Same journal

Ethical Considerations in Same-Day Surgical Treatment of a High-Risk, Poorly Differentiated Squamous Cell Carcinoma.

Journal of the American Academy of Dermatology·2026
Same journal

The Ethics of the Handshake in Dermatology.

Journal of the American Academy of Dermatology·2026
Same journal

Dermatology images: Hidradenitis suppurativa.

Journal of the American Academy of Dermatology·2026
See all related articles

Area of Science:

  • Virology
  • Molecular Biology
  • Immunology

Background:

  • Human Immunodeficiency Virus Type 1 (HIV-1) causes Acquired Immunodeficiency Syndrome (AIDS).
  • Understanding the viral replicative cycle is crucial for therapeutic development.

Purpose of the Study:

  • To elucidate the detailed steps of the HIV-1 replicative cycle.
  • To identify potential targets for antiviral chemotherapy.
  • To highlight challenges in developing effective HIV-1 treatments and vaccines.

Main Methods:

  • Review of existing research on HIV-1 biology and replication.
  • Analysis of the sequential stages of the viral life cycle.

Main Results:

  • Detailed description of the eight key stages in the HIV-1 replicative cycle, from attachment to viral release.

Related Experiment Videos

  • Identification of each stage as a potential target for antiviral drug development.

    • Conclusions:

    • While numerous antiviral drugs exist, none are fully effective against all HIV-1 infection stages.
    • Significant obstacles persist in the development of a broadly effective HIV-1 vaccine.