Interdisciplinary management of an isolated intrabony defect

Area of Science:

• Dentistry
• Periodontology
• Regenerative Medicine

Background:

• Intrabony defects in molars present a significant clinical challenge due to their chronic nature and potential to cause retrograde pulpitis.
• Extensive bone loss complicates the treatment of these periodontal lesions, necessitating advanced regenerative approaches.

Purpose of the Study:

• To evaluate the efficacy of combining endodontic treatment with a specific periodontal surgical approach for intrabony defects.
• To assess the bone regenerative potential of PepGen P-15 composite with platelet-rich plasma in molar intrabony defects.

Main Methods:

• The study involved endodontic treatment of the affected molar tooth.
• Periodontal surgery was performed to address the deep periodontal pocket and osseous defect.
• PepGen P-15 composite material combined with platelet-rich plasma was used as a graft for bone regeneration.

Main Results:

• The combined treatment approach aimed to eliminate periodontal disease and encourage bone fill within the defect.
• The utilization of PepGen P-15 and platelet-rich plasma demonstrated a synergistic effect, enhancing bone formation.
• Successful regeneration of the osseous defect was observed following the intervention.

Conclusions:

• The combined endodontic and periodontal surgical treatment is effective for managing complex intrabony defects in molars.
• PepGen P-15 composite with platelet-rich plasma shows promise as a synergistic graft material for enhanced bone regeneration in periodontal defects.