Related Experiment Video
Updated: Apr 19, 2026
05:31
Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
1.5K
[Plasma D-dimer levels in preeclampsia]
Akusherstvo I Ginekologiia
|December 17, 2014
Summary
Elevated D-dimer levels in the third trimester are linked to preeclampsia development. This finding suggests D-dimer may aid in diagnosing this pregnancy complication.
Area of Science:
- Obstetrics and Gynecology
- Hematology
- Pathophysiology
Context:
- Preeclampsia is a serious pregnancy complication marked by hypertension and proteinuria after 20 weeks.
- Fibrin deposition in small blood vessels is a key pathological feature of preeclampsia.
- D-dimer, a marker of fibrin degradation, is crucial in diagnosing thrombotic conditions.
Purpose:
- To investigate the association between plasma D-dimer levels and preeclampsia.
- To compare D-dimer concentrations in pregnancies with preeclampsia versus normal pregnancies.
Summary:
- This study evaluated plasma D-dimer levels in preeclamptic pregnancies compared to normal pregnancies.
- Results indicate elevated D-dimer levels are associated with preeclampsia in the third trimester.
- These preliminary findings suggest a potential role for D-dimer in preeclampsia assessment.
Impact:
- Highlights the potential diagnostic and prognostic value of D-dimer in preeclampsia.
- Underscores the need for further research to elucidate D-dimer's role in pregnancy complications.
- May lead to improved monitoring and management strategies for preeclampsia.
Related Concept Videos
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
450
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
450
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
721
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
721
01:29Pulmonary Embolism I: Introduction
1.4K
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
1.4K