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Updated: Apr 19, 2026

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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
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Transcaval access for TAVR across a polyester aortic graft
Robert J Lederman1, William W O'Neill2, Adam B Greenbaum2
1Cardiovascular and Pulmonary Branch, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Summary
This study demonstrates successful transcaval access through a synthetic aortic graft for transcatheter aortic valve replacement. A novel technique using radiofrequency energy enabled the procedure, with the resulting aorto-caval fistula closing spontaneously.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Medical Device Technology
Background:
- Transcaval access provides an alternative route for transcatheter aortic valve replacement (TAVR) when traditional access is not feasible.
- Closure of the aorto-caval fistula post-TAVR typically involves nitinol cardiac occluders.
- Previous literature lacks experience with transcaval access through synthetic aortic grafts.
Observation:
- A patient requiring TAVR had a history of aortic graft surgery, precluding standard access routes.
- Radiofrequency energy was utilized to facilitate guidewire traversal through a polyester aortic graft for retrograde venous access.
- A polyester-seeded nitinol ventricular septal defect occluder was implanted to close the aorto-caval fistula.
Findings:
- Successful transcaval access and TAVR were achieved through a polyester aortic graft.
- The described technique allowed for retrograde TAVR via the femoral vein.
- Initial residual aorto-caval fistulous flow resolved spontaneously within one month post-procedure.
Implications:
- This case expands the applicability of transcaval access for TAVR to patients with synthetic aortic grafts.
- The use of radiofrequency energy offers a potential solution for navigating prosthetic material during vascular access.
- Spontaneous closure of the aorto-caval fistula suggests favorable healing characteristics of the chosen occluder device.

