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Updated: Apr 19, 2026

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
Published on: April 19, 2024
How doctors learn and perform sustained inflations with a self-inflating bag: a manikin study with a newborn lung
Anne Marthe Boldingh1, Anne L Solevåg, Jūratė Šaltytė Benth
1Department of Paediatric and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway; Akershus Faculty Division, University of Oslo, Lørenskog, Norway.
Aim:
Sustained inflations during initial resuscitation may help a depressed infant make a more efficient transition to air-filled lungs. This study examined whether doctors could perform sustained inflations with a self-inflating bag in high and low compliance settings and with an open or blocked pressure-relief valve.
Methods:
We asked 43 doctors to carry out sustained inflations for more than 5-sec in a manikin connected to a newborn lung simulator with randomised compliance settings. Tidal volume, inflation time, peak and mean inflating pressure were measured, and 34 were retested 3 months later.
Results:
The majority of the doctors - 72% in the initial study and 62% in the retest - managed sustained inflations within three ventilation attempts, irrespective of lung compliance setting and years of work experience. Using a blocked pressure-relief valve produced higher tidal volume (27.8 versus 22.6 mL, p < 0.001), inflation time (8.9 versus 8.1 sec, p = 0.025), peak inflating pressure (34.0 versus 28.0 cmH2O; p = 0.012) and mean inflating pressure (28.1 versus 22.8 cmH2O; p < 0.001).
Conclusion:
The majority of doctors could deliver sustained inflation with a self-inflating bag in a newborn lung simulator for more than 5-sec. Using a blocked pressure-relief valve resulted in higher inflation time, tidal volume and inflation pressure.
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