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Updated: Apr 19, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
A new chromo-fluorogenic probe based on BODIPY for NO2 detection in air
L Alberto Juárez1, Ana M Costero, Margarita Parra
1Centro de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Unidad Mixta Universidad Politécnica de Valencia-Universidad de Valencia, Spain.
A new colorimetric probe was developed for detecting nitrogen dioxide (NO2) in both liquid and gas forms. This probe offers selective and sensitive detection, paving the way for improved environmental monitoring.
Area of Science:
- Analytical Chemistry
- Environmental Science
- Materials Science
Background:
- Nitrogen dioxide (NO2) is a significant air pollutant with adverse environmental and health impacts.
- Accurate and sensitive detection of NO2 is crucial for environmental monitoring and industrial safety.
- Existing detection methods may lack selectivity, sensitivity, or applicability in diverse environments.
Purpose of the Study:
- To synthesize and characterize a novel colorimetric probe for NO2 detection.
- To evaluate the probe's selectivity and sensitivity for NO2 in solution and air.
- To establish a new tool for real-time NO2 monitoring.
Main Methods:
- Synthesis of a novel BODIPY-based probe incorporating an oxime functional group.
- Spectrophotometric analysis to determine the probe's response to NO2.
- Testing the probe's performance in aqueous solutions and gaseous environments.
- Evaluation of probe selectivity against common interfering species.
Main Results:
- A novel BODIPY-core oxime probe was successfully synthesized.
- The probe exhibited a distinct colorimetric response upon interaction with NO2.
- High selectivity and sensitivity for NO2 detection were demonstrated in both solution and air.
- The probe showed rapid response and good stability.
Conclusions:
- The developed BODIPY-based oxime probe is a promising candidate for selective and sensitive NO2 detection.
- This probe offers a viable colorimetric method for environmental NO2 monitoring.
- Further development could lead to practical applications in air quality assessment and industrial safety.
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