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Acute renal failure following multiple wasp stings
Ghias Butt1, Kifayat Ullah1, Kinza Kanwal1
1Department of Nephrology, Pakistan Institute of Medical Sciences, Islamabad.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|December 19, 2014
Summary
Wasp stings can cause acute tubular necrosis (ATN), a rare kidney injury, due to direct venom toxicity. Early detection and treatment of this renal failure are crucial for complete recovery.
Area of Science:
- Nephrology
- Toxicology
- Immunology
Background:
- Acute tubular necrosis (ATN) is typically caused by ischemia or nephrotoxins.
- Wasp venom-induced ATN is exceptionally rare, with few documented cases.
Observation:
- Two cases of young males presenting with oliguria and severe renal dysfunction post-multiple wasp stings.
- Both patients required hemodialysis due to critically impaired kidney function.
Findings:
- Renal biopsies confirmed acute tubular necrosis (ATN) in both patients.
- Absence of casts and other specific changes suggested direct venom toxicity as the cause of ATN.
- Both patients achieved full renal recovery within weeks.
Implications:
- This study highlights the potential for direct wasp venom toxicity to cause severe acute kidney injury.
- Emphasizes the importance of prompt diagnosis and management of renal failure following wasp stings.
- Suggests further research into the specific nephrotoxic components of wasp venom.
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