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Updated: Apr 19, 2026
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Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
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Bifocal adult embryonal rhabdomyosarcoma
Syed Hassan Abbas Naqvi1, Muhammad Yasin Bandukda1, Syed Hassan Shiraz Naqvi2
1Department of Surgery, Dow Medical College, Dow University of Health Sciences, Civil Hospital, Karachi.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|December 19, 2014
Summary
Adult embryonal rhabdomyosarcoma is rare, but this case highlights successful treatment in a 36-year-old male. The patient achieved complete resolution of neck and trunk masses through surgery, chemotherapy, and radiotherapy.
Area of Science:
- Oncology
- Pathology
Background:
- Embryonal rhabdomyosarcoma (eRMS) is a rare soft tissue sarcoma.
- Typically diagnosed in pediatric patients, adult eRMS is exceptionally uncommon.
Observation:
- A 36-year-old male presented with two large, protruding masses on the left neck and lower trunk.
- Diagnostic biopsy and immunohistochemical studies confirmed eRMS.
Findings:
- The patient underwent a multimodal treatment approach.
- Treatment comprised surgical resection, chemotherapy, and radiotherapy, leading to complete mass resolution.
Implications:
- This case demonstrates the feasibility and effectiveness of combined-modality treatment for adult eRMS.
- Successful outcomes in rare adult presentations of embryonal rhabdomyosarcoma warrant further investigation and optimized therapeutic strategies.
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