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Published on: December 6, 2016
Severity of childhood obstructive sleep apnea and hypertension improved after adenotonsillectomy
Li-Ang Lee1, Hsueh-Yu Li2, Yu-Sheng Lin3
1School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan Department of Otolaryngology, Sleep Center, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan Department of Otolaryngology, Xiamen Chang Gung Hospital, Xiamen, China 5738@cgmh.org.tw.
Insights
Adenotonsillectomy improved childhood obstructive sleep apnea (OSA) and reduced hypertension rates. However, severe OSA and hypertension require ongoing blood pressure management post-surgery.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Pediatric Cardiology
Background:
- Childhood obstructive sleep apnea (OSA) is associated with significant comorbidities, including hypertension.
- Adenotonsillectomy is a primary treatment for pediatric OSA, but its impact on associated conditions like hypertension requires further investigation.
Purpose of the Study:
- To evaluate the effectiveness of adenotonsillectomy in improving obstructive sleep apnea (OSA) and hypertension in children.
- To assess changes in apnea-hypopnea index (AHI) and blood pressure (BP) post-surgery.
Main Methods:
- A case series of 50 consecutive pediatric patients with OSA undergoing plasma knife-assisted adenotonsillectomy.
- Assessment of body mass index z score, AHI, systolic BP, and diastolic BP at baseline and at least 6 months postoperatively.
- Statistical analysis using nonparametric tests with bootstrap approach.
Main Results:
- Adenotonsillectomy significantly reduced the median apnea-hypopnea index (AHI) from 9.8 to 1.6 (P<.001).
- The overall hypertension rate decreased significantly from 34% to 14% (P=.006).
- Significant reductions in systolic and diastolic blood pressure were observed in children with preoperative hypertension (P=.038 and P=.005, respectively).
Conclusions:
- Adenotonsillectomy effectively reduces OSA severity and hypertension rates in children.
- While surgical intervention improves OSA, persistent hypertension in severe cases necessitates continued blood pressure management.
- The reduction in AHI alone may not fully resolve hypertension, highlighting the multifactorial nature of this comorbidity.
Objective:
To report improvements in childhood obstructive sleep apnea (OSA) and hypertension after adenotonsillectomy.
Study Design:
Case series with planned data collection.
Setting:
Tertiary referral center.
Subjects And Methods:
Fifty consecutive patients (36 boys and 14 girls; median age, 7.0 years) who underwent plasma knife-assisted total tonsillectomy and adenoidectomy for OSA between January 2010 and March 2013 were assessed with the body mass index z score, apnea-hypopnea index (AHI), systolic blood pressure (BP), and diastolic BP at baseline and at ≥6 months postoperatively. Changes in these parameters were statistically analyzed using nonparametric tests with the bootstrap approach.
Results:
The median follow-up period was 9.6 months. Postoperatively, the median AHI significantly reduced from 9.8 to 1.6 (P<.001). Although the median systolic BP and diastolic BP insignificantly changed in the overall group, both were significantly reduced in children with preoperative hypertension (systolic: from 119.0 to 113.0 [P=.038]; diastolic: from 79.0 to 68.0 [P=.005]). Accordingly, the hypertension rate significantly reduced from 34% to 14% (P=.006). However, the change in OSA severity was not well correlated with the change in hypertension severity. In multiple logistic regression analysis with forward selection, a combination of preoperative hypertension and severe OSA was a significant predictor of postoperative hypertension (relative risk, 15.4; 95% confidence interval, 3.7-64.3; P<.001).
Conclusion:
The decreased hypertension rate indicates that a reduction of the AHI is not all that matters after adenotonsillectomy in childhood OSA. However, patients with preoperative severe OSA and hypertension need careful management of their elevated BP despite surgical treatment.
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