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[Cost-effectiveness analysis (CEA) regarding vitamin A in children aged less than 5 years-old in Colombia]
Hoover Quitian1, Natalia Castaño1, Claudia Granados1
1Departamento de Epidemiología Clínica y Bioestadística, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia, quitianh@javeriana.edu.co.
Insights
Vitamin A supplementation in children under 5 is a cost-effective strategy, significantly reducing diarrhea and malaria cases. This approach saves money for the Colombian health system by preventing illnesses and hospitalizations.
Area of Science:
- Public Health
- Health Economics
- Pediatrics
Background:
- Vitamin A deficiency is a significant public health concern in developing countries.
- Diarrhea and malaria are leading causes of childhood mortality.
- Effective interventions are crucial for reducing the burden of these diseases.
Purpose of the Study:
- To evaluate the cost-effectiveness of vitamin A supplementation for children under 5.
- To assess the impact on diarrhea, malaria, and mortality within the Colombian health system.
Main Methods:
- A decision tree model was used to estimate deaths averted.
- Probabilities were sourced from existing literature, and costs from official Colombian data.
- Sensitivity analyses and cost-effectiveness acceptability curves were employed.
Main Results:
- Supplementing 100,000 children with vitamin A resulted in cost savings of over $340 million.
- Significant reductions were observed in diarrhea (4,268 events) and malaria (76 events).
- Reduced hospitalizations contributed to overall cost-effectiveness.
Conclusions:
- Vitamin A supplementation is a dominant strategy for the Colombian health system.
- It is the most cost-effective and effective intervention compared to no supplementation.
- This highlights the value of vitamin A in child health programs.
Objective:
Evaluating the relative cost-effectiveness of using vitamin A in children aged less than 5-years-old regarding the reduction of events involving diarrhoea, malaria and mortality from the Colombian health-related social security system (CHSSS).
Materials And Methods:
A decision tree was constructed, using deaths averted as outcome. Probabilities were taken from the pertinent literature and costs from official sources. The cost-effectiveness threshold was three times greater than the per capita Colombian gross domestic product (GDP) in 2012. Probabilistic and deterministic sensitivity analyses were made and cost effectiveness acceptability curves were drawn.
Results:
Providing a cohort of 100,000 children with vitamin A (as opposed to not doing so) would represent a saving regarding medical attention costs of $ 340,306,917 due to the number of events involving diarrhea (4,268) and malaria (76), having become reduced, as well as cases requiring hospitalization. A saving for the CHSSS was consistently obtained in sensitivity analysis.
Conclusion:
Providing vitamin supplements for children aged less than 5 years-old would seem to be the least costly and most effective (dominant) strategy for the CHSSS, i.e. compared to not doing so).
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