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Published on: November 10, 2014
Ultrasound-guided percutaneous laser ablation in treating symptomatic solid benign thyroid nodules: Our experience in
Gaetano Achille1, Stefania Zizzi2, Enrico Di Stasio3
1Cervico-Facial Ultrasound Diagnostic and Interventional Unit, Institute of Oncology, Bari, Italy.
Background:
Laser ablation may be useful in debulking of benign thyroid nodules.
Methods:
In order to retrospectively evaluate the effectiveness and safety of laser ablation, 45 patients with benign solid thyroid nodules, with a fluid component ≤20%, were included in our series between October 2009 and January 2011. All reported pressure and/or cosmetic complaints. Nd:YAG laser at 1064 nm was used, with a fix-power (3W), changing the application time. All patients were evaluated at baseline, 6 months, and 12 months and any complications were recorded.
Results:
Mean nodule volume reduction decreased from 24.2 mL ± 19.4 to 4.5 ± 5.2 at 12 months (p < .001). Mean nodule volume reduction was 84% ± 13. Cosmetic signs were completely resolved in 87%, reduced in 9%, unchanged in 2%, and pressure symptoms were resolved in 88%. One patient experienced transient dysphonia.
Conclusion:
Ultrasound-guided laser ablation is an effective tool for treatment of symptomatic benign thyroid nodules in patients not eligible for surgery.
