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Medication non-adherence in essential tremor.

Elan D Louis1

  • 1GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA; Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA.

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|December 20, 2014
PubMed
Summary
This summary is machine-generated.

Nearly one in four essential tremor (ET) patients report missing whole days of medication. This high non-adherence may stem from the limited effectiveness of current ET treatments.

Keywords:
AdherenceClinicalComplianceEpidemiologyEssential tremorTreatment

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Area of Science:

  • Neurology
  • Clinical Epidemiology
  • Pharmacology

Background:

  • Medication adherence is widely studied in chronic diseases like Parkinson's, but not in essential tremor (ET).
  • Essential tremor affects millions, yet adherence data is lacking.
  • Understanding adherence is crucial for effective chronic disease management.

Purpose of the Study:

  • To report self-assessed medication adherence in essential tremor patients.
  • To identify demographic and clinical factors linked to poor adherence in ET.

Main Methods:

  • 151 essential tremor patients participated in a clinical-epidemiological study.
  • A validated 11-item questionnaire assessed medication adherence.
  • Factor analysis explored patterns of non-adherence.

Main Results:

  • 48.3% of ET patients used daily medication; 23.3% reported missing entire days of medication in the past two weeks.
  • Higher non-adherence correlated with depressive symptoms, younger age, and less severe tremor.
  • Non-adherence was not associated with the type or number of ET medications used.

Conclusions:

  • A significant proportion of essential tremor patients exhibit substantial medication non-adherence.
  • This high rate may indicate dissatisfaction with current ET medication efficacy.
  • Further research into adherence barriers and treatment effectiveness is warranted.