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[Quantitative computed tomographic flow measurements of aortocoronary venous bypass grafts. II. Correlation with
V Mühlberger1, N Moes, D zur Nedden
1Univ.-Klinik für Innere Medizin, Innsbruck.
Insights
Computed tomography (CT) can assess aortocoronary venous bypass grafts (ACVB) flow, but accuracy is limited. Maximum contrast medium concentration decrease on CT correlated significantly with invasive angiography flow rates.
Area of Science:
- Cardiovascular Imaging
- Medical Physics
Background:
- Aortocoronary venous bypass grafts (ACVB) are crucial for myocardial revascularization.
- Accurate assessment of graft patency and flow is essential for patient outcomes.
- Non-invasive methods for quantitative flow assessment in ACVB are highly desirable.
Purpose of the Study:
- To compare quantitative invasive angiographic parameters with contrast medium flow parameters assessed by computed tomography (CT) in ACVB.
- To evaluate the accuracy of CT in determining quantitative flow within ACVB.
Main Methods:
- Quantitative invasive angiography was performed in 26 patients with 35 ACVB.
- Contrast medium flow parameters were assessed using CT with a 3-second repetition rate.
- Seven different CT parameters were analyzed and correlated with angiographic flow rates.
Main Results:
- The maximum decrease in contrast medium concentration on CT (40 +/- 5 HE/sec) showed a significant correlation (r = 0.536, p < 0.001) with the quantitative flow rate measured by invasive angiography (7.2 +/- 0.5 cm/sec).
- This correlation indicates a relationship between CT-derived contrast dynamics and actual graft flow.
- Despite the significant correlation, the standard error of estimate (SEE = 23.17) suggests limited precision.
Conclusions:
- Computed tomography with a 3-second repetition rate can provide a significant correlation with invasive angiography for quantitative flow assessment in ACVB.
- However, the accuracy for single-patient assessment of quantitative flow in ACVB using this CT method is limited.
- Further advancements in CT technology may be needed to improve the precision of non-invasive graft flow quantification.
Abstract:
In 26 patients with 35 aortocoronary venous bypass grafts (ACVB) quantitative invasive angiographic parameters were compared with flow parameters of contrast medium, assessed by computed tomography. Out of seven different CT-parameters, the maximum decrease of concentration of contrast medium (40 +/- 5 HE/sec; mean +/- SEM) showed a correlation with the angiographic parameter of contrast medium quantitative flow rate (7.2 +/- 0.5 cm/sec) and this correlation (r = 0.536/SEE = 23.17) is significant (p less than 0.001). We conclude that for the single patient assessment of quantitative flow in ACVB by CT with a 3-second repetition rate could be performed with limited accuracy.