Related Experiment Video
Updated: Apr 19, 2026

Laparoscopic Anatomical Resection of the Right Anterior Lobe Based on the Laennec Capsule Technique
Published on: May 2, 2025
Hepatocellular carcinoma to the right ventricle
George R Marzouka1, Apurva Badheka1, Alexis P Rodriguez2
1Division of Cardiology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Clinical Research Building, Room 1107, Miami, FL 33136, USA.
This case report details a rare instance of hepatocellular carcinoma (HCC) metastasizing to the heart in a patient with a history of hepatitis C and cirrhosis. The cardiac mass was diagnosed via imaging and biopsy, leading to hospice care.
Area of Science:
- Oncology
- Cardiology
- Hepatology
Background:
- Hepatocellular carcinoma (HCC) is a globally prevalent cancer.
- Cardiac metastasis from HCC is exceptionally rare.
- This case involves a patient with a history of hepatitis C, cirrhosis, and prior liver transplants.
Purpose of the Study:
- To report a rare case of cardiac metastasis of hepatocellular carcinoma.
- To highlight the diagnostic findings and clinical presentation of this rare event.
Main Methods:
- Case presentation of a 63-year-old male with advanced HCC.
- Diagnostic imaging including transthoracic echocardiogram and cardiac MRI.
- Biopsy of the cardiac mass for histopathological confirmation.
Main Results:
- A large, irregular mass (4.4 × 3.4 × 4.0 cm) was identified in the right ventricular apex.
- Histopathology confirmed moderately differentiated HCC with myocardial involvement.
- Clinical presentation included lower extremity edema and cardiac murmur.
Conclusions:
- Cardiac metastasis of HCC, though rare, can occur in patients with advanced liver disease.
- Multimodality imaging and biopsy are crucial for diagnosis.
- Management often involves supportive care and hospice due to advanced disease.
Related Concept Videos
Cardiac Catheterization II: Right Heart Catheterization
Mitral Regurgitation I: Introduction
Cardiomyopathy IV: Restrictive Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Mitral Stenosis I: Introduction

