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Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

Multiparametric MRI-targeted TRUS prostate biopsies using visual registration.

Philippe Puech¹, Adil Ouzzane², Vianney Gaillard³

¹Department of Radiology, Lille University Hospital, Lille University, 59000 Lille, France ; Inserm U703, 59120 Loos, France.

Biomed Research International

|December 20, 2014

Summary

Cognitive, visually-registered transrectal ultrasound-guided (TRUS-G) target biopsies (TB) offer a simple method for diagnosing clinically significant prostate cancer (CSPCa). This approach aids in avoiding overtreatment of prostate cancer (PCa).

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Area of Science:

Urology
Radiology
Oncology

Background:

Multiparametric prostate MRI (mp-MRI) followed by transrectal ultrasound-guided (TRUS-G) target biopsies (TB) is crucial for diagnosing clinically significant prostate cancer (CSPCa).
This combination helps prevent overtreatment of prostate cancer (PCa).
Various guidance techniques exist for TB, with cognitive registration being the simplest and most accessible.

Purpose of the Study:

To review the method of cognitive, visually-registered mp-MRI-targeted biopsies (TB).
To detail the steps involved in optimizing this diagnostic approach.
To discuss the indications and diagnostic yield of mp-MRI-targeted biopsies.

Main Methods:

Detailed review of the successive steps in cognitive TB: target detection, mp-MRI reporting, intermodality fusion, TRUS guidance, sampling simulation, sampling, and reporting.
Discussion on optimizing each step for improved accuracy and efficiency.
Comparison of diagnostic yield between visually-registered TB and conventional biopsies or other registration methods.

Main Results:

Cognitive registration is presented as the simplest, cheapest, and easiest-to-learn method for guiding TB to mp-MRI targets.
The review outlines methods to optimize each stage of the cognitive TB procedure.
Diagnostic yield of visually-registered TB is discussed in comparison to alternative biopsy techniques.

Conclusions:

Cognitive, visually-registered mp-MRI-TB is a valuable and accessible technique for diagnosing CSPCa.
Optimization of procedural steps can enhance the diagnostic performance of this method.
This approach offers a viable alternative for accurate prostate cancer diagnosis, potentially reducing overtreatment.