Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

7
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
7
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

2
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
2

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Innovative Integration of Robotic-Assisted Laparoscopic Telesurgery and Quantum Cryptography Communication in Urology: Clinical Application and Initial Experience.

The international journal of medical robotics + computer assisted surgery : MRCAS·2025
Same author

Incremental yield of prenatal exome sequencing in fetuses with skeletal system abnormalities: A systematic review and meta-analysis.

Acta obstetricia et gynecologica Scandinavica·2024
Same author

Highly efficient narrow bandgap Cu(In,Ga)Se<sub>2</sub> solar cells with enhanced open circuit voltage for tandem application.

Nature communications·2024
Same author

Single-cell RNA sequencing analysis reveals the role of TXNDC5 in keloid formation.

CytoJournal·2024
Same author

A pan-orthoebolavirus neutralizing antibody encoded by mRNA effectively prevents virus infection.

Emerging microbes & infections·2024
Same author

Protection against cigarette smoke-induced chronic obstructive pulmonary disease via activation of the SIRT1/FoxO1 axis by targeting microRNA-132.

American journal of translational research·2024

Related Experiment Video

Updated: Apr 19, 2026

C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position
12:25

C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position

Published on: September 16, 2022

4.9K

Multiple-level lumbar spondylolysis and spondylolisthesis.

Xinyu Liu1, Lianlei Wang, Suomao Yuan

  • 1Department of Orthopedic Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China.

Journal of Neurosurgery. Spine
|December 20, 2014
PubMed
Summary

Multiple-level lumbar spondylolysis and spondylolisthesis, though rare, were successfully treated with standard surgical techniques. This condition, more common in men, often involves two spinal levels and is linked to physical activities.

Keywords:
JOA = Japanese Orthopaedic AssociationVAS = visual analog scalelumbar spinemultiple-levelspondylolisthesisspondylolysis

More Related Videos

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

1.7K
Lateral-PLIF for Lumbar Spinal Arthrodesis: A Detailed Step-By-Step Surgical Technique
08:36

Lateral-PLIF for Lumbar Spinal Arthrodesis: A Detailed Step-By-Step Surgical Technique

Published on: January 23, 2026

330

Related Experiment Videos

Last Updated: Apr 19, 2026

C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position
12:25

C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position

Published on: September 16, 2022

4.9K
Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

1.7K
Lateral-PLIF for Lumbar Spinal Arthrodesis: A Detailed Step-By-Step Surgical Technique
08:36

Lateral-PLIF for Lumbar Spinal Arthrodesis: A Detailed Step-By-Step Surgical Technique

Published on: January 23, 2026

330

Area of Science:

  • Orthopedic Surgery
  • Spinal Disorders
  • Radiology

Background:

  • Lumbar spondylolysis and isthmic spondylolisthesis typically affect a single spinal level.
  • Multiple-level involvement is less common but presents unique diagnostic and treatment challenges.

Purpose of the Study:

  • To report on the characteristics and treatment outcomes of 13 patients with multiple-level lumbar spondylolysis and spondylolisthesis.
  • To evaluate the efficacy of surgical interventions for this condition.

Main Methods:

  • Retrospective review of 13 patients diagnosed with multiple-level spondylolysis and spondylolisthesis between July 2007 and March 2012.
  • Analysis of patient demographics, pain duration, affected spinal levels, and surgical procedures (pedicle screw fixation, interbody fusion, or pars interarticularis repair).
  • Assessment of pre- and post-operative outcomes using the Japanese Orthopaedic Association score and visual analog scale for pain.

Main Results:

  • All patients experienced significant improvement in low-back pain after surgery.
  • Postoperative imaging confirmed successful interbody fusion or pars interarticularis healing.
  • No hardware complications such as breakage or loosening were reported.

Conclusions:

  • Multiple-level lumbar spondylolysis and spondylolisthesis are more prevalent in men and often involve two spinal levels.
  • This condition is frequently associated with sports, trauma, or heavy labor, commonly affecting L3-5 levels.
  • Surgical treatment principles for multiple-level disease are consistent with those for single-level spondylolisthesis.