Related Experiment Video
Updated: Apr 19, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Assessment of vitamin D status in children aged 1-5 with simple obesity
Insights
Young children, especially those who are obese, are at risk of vitamin D deficiency due to low intake. Obese children are particularly vulnerable in autumn and winter, necessitating monitoring of vitamin D status.
Area of Science:
- Pediatric Endocrinology
- Nutritional Science
- Public Health
Background:
- Vitamin D plays a crucial role due to its widespread effects.
- Obese populations are identified as a high-risk group for vitamin D deficiency.
- Understanding vitamin D status in children is vital for growth and development.
Purpose of the Study:
- To evaluate the vitamin D status in 1-5-year-old children with simple obesity.
- To compare vitamin D levels between obese and non-obese children.
- To assess the impact of season and intake on vitamin D status.
Main Methods:
- A study involving 100 children aged 1-5, divided into obese (n=50) and non-obese (n=50) groups based on BMI.
- Serum 25-hydroxyvitamin D (25(OH)D) concentrations were measured across seasons (spring-summer, autumn-winter).
- Vitamin D intake from diet and supplements was assessed, with statistical analysis performed.
Main Results:
- Mean serum 25(OH)D levels were 23.6±10.8 ng/ml in obese children versus 26.6±9.8 ng/ml in non-obese children (p=0.08).
- 80% of obese children and 70% of non-obese children had levels ≤30 ng/ml.
- Insufficient vitamin D status was observed in 88.5% of obese children during autumn-winter compared to 70.9% in spring-summer (p=0.002).
- Mean daily vitamin D intake was lower in obese children (128 IU) than non-obese (188 IU).
Conclusions:
- Children aged 1-5, both obese and non-obese, are at risk of vitamin D deficiency due to inadequate intake and supplementation.
- Obese children face a heightened risk, particularly during the autumn-winter season.
- Regular monitoring of vitamin D status in children aged 1-5 is recommended.
Background:
Proper vitamin D intake is important due to its pleiotropic effect. It seems that obese population is a groups at risk of the vitamin D deficiency.
Objective:
To assess the vitamin D status in 1-5-year-old children with simple obesity.
Materials And Methods:
The study included 100 children: classified according to their body mass index (BMI) as obese - Group I (n=50) and non-obese - Group II (n=50). Their serum 25-hydroxyvitamin D (25(OH)D) concentrations were determined in the spring-summer and autumn-winter seasons and vitamin D intake (diet/supplements) was assessed. The study results were statistically analysed by means of Statistica 10PL.
Results:
In Group I the mean serum 25(OH)D level was 23.6±10.8 ng/ml, while in Group II it reached 26.6±9.8 ng/ml (p=0.08). The concentration ≤30 ng/ml was observed in 80% of children in Group I and in 70% of Group II. In autumn- winter and spring-summer period, respectively, 88.5% and 70.9% of the obese children had an insufficient vitamin D status (p=0.002). The mean daily intake of vitamin D was 128 IU (3.2 µg) in Group I and 188 IU (4.7 µg) in Group II.
Conclusions:
Children aged 1-5 (obese and non-obese) are a group at risk of the vitamin D deficiency, as a consequence of its insufficient intake and the lack of appropriate supplementation. Those particularly exposed to that risk are obese children in the autumn-winter season. Children aged 1-5 should be monitored with regard to their vitamin D status.
Key Words:
vitamin D, obesity, children, obese children, vitamin D deficiency.
Related Concept Videos
Obesity
Drug Dosing: Obese Patients
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
Drug Dosing: Infants and Children
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion